No matter how good 3D bio-printing technology is, don't print cells easily.

As 3D bioprinting continues to show broad prospects, cosmetics companies are beginning to explore the potential of 3D printing in skin care applications. However, Nissho Global Information Co., Ltd. called for Lux Research Arnaold Bos to be cautious because print cell controllability is too low.

3D bioprinting is a process that uses 3D printing technology to stimulate biologically controlled cell patterns, and cell function and viability can be preserved in printed structures.

As more and more cosmetic manufacturers enter the field, Bos warns that printing cells will face the challenge of raw materials and printing costs, and the biggest challenge that beauty companies will encounter is biological understanding.

Arnaold Bos told CosmeticDesign-Asia that the skin is complex – an acid-base level error or a temperature error can cause the model to fail. Industry regulators in this area also need to work with industry to provide transparency and guidelines.

“Plastic 3D printing technology can be used for bioprinting, but in the event of cell problems or any changes in the printing process, it is difficult for the experimenter to detect or correct the problem.”

What are the potential possibilities?

If 3D bioprinting technology is used properly and correctly, it can provide accurate skin modeling for safety and effectiveness testing, opening a new world for cosmetic skincare verification testing. The test article can be customized in the laboratory in advance to shorten the time to verify that the chemical equation is valid.

Bos believes that the more interesting applications of 3D printing on this road will include the development of more customized and personalized cosmetics by constructing well-characterized skin models such as dry and oily skin, different ethnic skin types.

Earlier this year, cosmetics companies such as L'Oreal and the US 3D bioprinter Organovo reached a cooperation agreement, the two sides will cooperate to develop 3D printed skin tissue.

Procter & Gamble also joined the ranks, announced the cooperation with the Science and Technology Research and Development Bureau of the Xinjiapi government, launched the award-winning technology collection competition, and invited professional scholars to submit 3D bioprinting applications related to P&G, with a prize of US$44 million.

3D bioprinting industry cooperation

Chemical giant BASF has signed a collaborative R&D agreement with Poietis, the world's first laser-assisted bioprinting company, to combine Poietis' 3D bioprinting technology with BASF's existing technology in an effort to improve BASF's skin equivalent model, Jameskin. Poietis uses a 3D laser-assisted bioprinting technology that creates organic tissue in a layer-by-layer manner and precisely positions the skin cells in a three-dimensional structure with the aid of a laser. Through this technology, cells will be able to grow in BASF's Mimeskin and eventually become the closest tissue closest to human primordial skin.

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